AstraZeneca's Rare Disease Drug Shows Reduced Dependence On Calcium Supplements

AstraZeneca plc (NASDAQ:AZN) on Tuesday said its investigational therapy eneboparatide met the primary endpoint in the Phase 3 CALYPSO trial in adults with chronic hypoparathyroidism, demonstrating statistically significant improvement in calcium control while reducing dependence on supplements.

The late-breaking data were presented at the European Congress of Endocrinology in Prague, Czech Republic.

Hypoparathyroidism is a rare condition in which the parathyroid glands in the neck produce too little parathyroid hormone (PTH), leading to low blood calcium (hypocalcemia) and high phosphorus levels.

Treatment involves calcium and vitamin D supplements.

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Eneboparatide Met Primary Endpoint

The CALYPSO trial evaluated eneboparatide, also known as AZP-3601, a parathyroid hormone 1 receptor agonist designed for patients with chronic hypoparathyroidism.

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AstraZeneca's Rare Disease Drug Shows Reduced Dependence On Calcium Supplements

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