Takeda Pharmaceutical Company Limited (NYSE:TAK) on Thursday shared topline results for the Phase 3 comparing zasocitinib (TAK-279) to Bristol-Myers Squibb Co.’s (NYSE:BMY) Sotyktu (deucravacitinib) in adults with moderate-to-severe plaque psoriasis (PsO).

Head-To-Head Trial Meets Endpoints

In the LATITUDE Atlas head-to-head study, zasocitinib demonstrated statistical superiority over deucravacitinib for the primary endpoint, Psoriasis Area and Severity Index (PASI) 100 response rate at week 16.

The study also demonstrated statistical superiority over deucravacitinib for all key secondary endpoints, including PASI 90 response and Static Physician’s Global Assessment (sPGA) 0 at week 16.

Zasocitinib was generally well tolerated with a consistent safety and tolerability profile and no new safety signals identified.

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